Place of birth: Lisbon, Portugal date of birth: July 17th, 1949 qualifications



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CURRICULUM VITAE
NAME: Pedro Jorge Macedo de Abreu

PLACE OF BIRTH: Lisbon, Portugal

DATE OF BIRTH: July 17th, 1949

QUALIFICATIONS: Licence Degree in Chemistry, University of Brussels, 1975

PhD in Chemistry, New University of Lisbon, 1987



PRESENT POSITION: Professor at the Chemistry Department of Faculty of Science and Technology, New University of Lisbon.

PROF. MEMBERSHIP: Portuguese Chemical Society; Phytochemical Society of Europe; American Society of Pharmacognosy; RIPROFITO (Iberamerican Network of Phytopharmaceutical Products).

INTERNATIONAL EDITORIAL BOARD

Marine Drugs



URL: http://www.dq.fct.unl.pt/QOA/abreu

RESEARCH INTERESTS

Natural Products Chemistry: isolation and characterization of natural products from sponges, algae, fungi and medicinal plants; biological evaluation. Pharmacognosy. Medicinal Plants.



RELATED WORK EXPERIENCE

  • Research Fellow at the Laboratory of Molecular Structural Chemistry, Namur University (1980).

  • NATO Research Fellow at the Bio-Organic Chemistry Department, Brussels University (1982).

  • Post-doc Research Fellow at the Faculty of Agriculture, University of Tokyo (1987).

RESEARCH PROJECTS UNDER CONTRACT

  • "Natural products from algae from the portuguese coast” (1989).

  • "Natural products from medicinal plants from Guinea-Bissau” (1992).

  • “Detection and isolation of antibiotic and antitumoral compounds from extracts from medicinal plants from Guinea-Bissau” (1997).

  • “Bioassay -guided isolation and identification of anti.inflammatory and antioxidant compounds from a medicinal extract of Pedilanthus tithymaloides” (2005-)

PUBLICATIONS

  1. "Luminescence Studies in Polymers, part X. Triplet energy migration in copolymers Styrene-vinylbenzophenone. Decay-time and its relation to phosphorescence emission and excitation spectra", C.David, D.Bayens-Volant, P.Macedo de Abreu, G.Gueskens, Europ. Polym. J. 13, 841-846 (1977).

  2. "Cavernosine, a novel ichthyotoxic terpenoid lactone from the sponge Fasciospongia cavernosa", J.C.Braekman, D.Daloze, R.Bertau, P.Macedo de Abreu, Bull. Soc. Chim. Belg. 91, 791-796 (1982).

  3. "A novel type of bis-quinolizidine alkaloid from the sponge Petrosia seriata", J.C.Braekman, D.Daloze, P.Macedo de Abreu, C.Piccinni-Leopardi, G.Germain, M.Van Meerssche, Tetrahedron Letters, 4277-4280 (1982).

  4. "Pisolactone, a novel triterpenoid isolated from the fungus Pisolithus tinctorius", Ana M.Lobo, P.Macedo de Abreu, Sundaresan Prabhakar, Lício S.Godinho, Tetrahedron Letters, 2205-2208 (1983).

  5. "Novel triterpenoids from the fungus Pisolithus tinctorius", Ana M.Lobo, P.Macedo de Abreu, Sundaresan Prabhakar, Lício Godinho, Henry S.Rzepa, Richard N.Sheppard, Tetrahedron Letters, 2589-2592 (1985).

  6. "Triterpenoids of the fungus Pisolithus tinctorius", Ana. M.Lobo, P.Macedo de Abreu, Sundaresan Prabhakar, Lício Godinho, Ray Jones, Henry S.Rzepa, David J.Williams, Phytochemistry, 27, 3569-3574 (1988).

  7. "Brassinosteroids: a new group of phytohormones", Pedro Abreu, Químca Nova, 1, 44-48 (1991).

  8. "Revision of C-22,23 configurations of two triterpenoids of the fungus Pisolithus tinctorius, P.Macedo de Abreu, Ana M.Lobo, Sundaresan Prabhakar, Phytochemistry, 30, 3818-3819 (1991).

  9. "Chemical constituents of Parkia biglobosa", M.E.M.Araújo, F.M.S.B.Palma, A.T.Moutinho, P.M.Abreu, Fitoterapia, 5, 468 (1995).

  10. “Constituents of Tephrosia uniflora”, Pedro M.Abreu and Maria H.Luis, Natural Product Letters, 9, 81-86 (1996).

  11. “Polyhalogenated monoterpenes from Plocamium cartilagineum from the Portuguese coast”, Pedro M.Abreu and José M.Galindro, Journal of Natural Products, 59, 1159-1162 (1996).

  12. “Volatile constituents of the rhizomes of Aframomum alboviolaceum (Ridley) K.Schum. from Guinea-Bissau, Pedro M.Abreu and Rita G.Noronha, Flavour and Fragrance Journal 12, 79-83 (1997).

  13. “Non-terpenoid compounds from Plocamium cartilagineum”, Pedro M.Abreu, José M. Galindro, Angela M. Relva and Ana M. Ramos, Phytochemistry, 45, 1601-1603 (1997).

  14. “Chemical composition of Lactarius controversus, a basidiomycetes fungus”, Abreu P, Araújo ME, Fonseca T, dos Santos SP, Pharm. Pharmacol. Letters, 7, 138-140 (1997).

  15. “A new indole alkaloid from Sarcocephalus latifolius", Pedro M. Abreu, António Pereira, Heterocycles, 48, 885-891 (1998).

  16. "Phytochemical analysis and antimicrobial evaluation of Detarium microcarpum bark extracts", P.M. Abreu, V.S. Rosa, E.M. Araujo, A.B. Canda, O. Kayser, K.-U. Bindseil, K. Siems and A. Seemann, Pharm. Pharmacol. Letters, 8, 107-109 (1998).

  17. "A new polyhalogenated epoxymonoterpene from Plocamium cartilagineum", Pedro M. Abreu and José Galindro, Indian J. Chemistry, 37B, 610-611 (1998).

  18. "Antimicrobial, Antitumor and Antileishmania Screening of medicinal Plants from Guinea-Bissau", P. M. Abreu, E. S. Martins, O. Kayser, K. -U. Bindseil, K. Siems, A. Seemann and J. Frevert, Phytomedicine, 6, 187 (1999).

  19. “New trichothecenes isolated from Holarrhena floribunda stem”, Ali Loukaci, O. Kayser, K.-U. Bindseil, K. Siems, J. Frevert and Pedro Abreu, Journal of Natural Products, 63, 52-56 (2000).

  20. “Characterisation of a sugar fraction from Sarcocephalus latifolius stem bark extract”, P. Abreu, A. Relva and A. Pereira, Carbohydrate Polymers, 45, 155-160 (2001).

  21. "New indole alkaloids from Sarcocephalus latifolius”, Pedro M. Abreu and António Pereira, Nat. Prod. Letters, 15, 43-48 (2001).

  22. "Antileishmanial and immunostimulating activities of two dimeric proanthocyanidins from Khaya senegalensis", O. Kayser and P.M. Abreu, Pharmaceutical Biology, 39, 284-288 (2001).

  23. "Carbohydrates from Detarium microcarpum bark extract", Pedro Abreu and Angela Relva, Carbohydrate Research, 337, 1663-1668 (2002).

  24. "Étude biologique et chimique de la plante Prasium major poussant en Tunisie. Structure d'un heteroside steroidique et d'un steroide. Identification de constituents de la fraction volatile", M.A. Mahjoub, H. Ben Jannet, P.J.M. Abreu, Z. Mighri, J. Soc. Chim. Tun., 4, 1419-1426 (2002).

  25. "Triterpenoids from the fruit barks of Periploca laevigata growing in Tunisia", F. Hichri, O. Hammouda, H. Ben Jannet, Z. Mighri, P.M. Abreu, J. Soc. Chim. Tun., 4, 1565-1569 (2002).

  26. "Three New Jatrophane-Type Diterpenes from Euphorbia pubescens", Cláudia Valente, Maria José U. Ferreira, Pedro M. Abreu, Madalena Pedro, Fátima Cerqueira, Maria São José Nascimento, Planta Medica, 69, 361-366 (2003).

  27. "Natural product-like combinatorial libraries", Pedro M Abreu and Paula S. Branco, J. Braz. Chem. Soc., 14, 675-712 (2003).

  28. "Triterpénes isolés des écorces des fruits de la plante Periploca laevigata poussant en Tunisie", F. Hichri, H. Ben Jannet, P.M. Abreu, Z. Mighri, J. Soc. Alg. Chim., 13, 187-196 (2003).

  29. “Rearranged jatrophane-type diterpenes from Euphorbia species. Evaluation of their effects on the reversal of multidrug resistance”, A. M. Madureira, Maria-José U. Ferreira, N. Gyémánt, K. Ugocsai, José R. Ascenso, Pedro M. Abreu, J. Hohmann, J. Molnar, Planta Medica, 70, 45-49 (2004).

  30. “Pubescenes, jatrophane diterpenes, from Euphorbia pubescens, with multidrug resistance reversal activity on mouse lymphoma cells, C. Valente, Maria-José U. Ferreira, Pedro M. Abreu, N. Gyémánt, K. Ugocsai, J. Hohmann, J. Molnar, Planta Medica, 70, 81-84 (2004).

  31. "Euphopubescenol and Euphopubescene, Two New Jatrophane Polyesters, and Lathyrane-type diterpenes from Euphorbia pubescens", Cláudia Valente, Madalena Pedro, José R. Ascenso, Pedro M. Abreu, Maria São José Nascimento and Maria-José U. Ferreira, Planta Medica, 70, 244-249 (2004).

  32. “Effect of cycloartanes on reversal of multidrug resistance and apoptosis induction on mouse lymphoma cells”, A. M. Madureira, G. Spengler, A. Molnar, A. Varga, J. Molnar, Pedro M. Abreu, Maria-José U. Ferreira Anticancer Res., 24 (2B), 859-864 (2004).

  33. “Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens, C. Valente, M. Pedro, A, Duarte, M. S. J. Nascimento, Pedro M. Abreu, and Maria-José U. Ferreira, Journal of Natural Products, 67, 902-904 (2004).

  34. A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein, Ana M. Madureira, Annamária Molnár, Pedro M. Abreu, Joseph Molnár, Maria-José U. Ferreira, Planta Medica, 70 , 828-833 (2004).

  35. “Structure d’un coumarino-lignane isolé de la partie aérienne de la plante Salsola tetrandra”, M. M. Oueslati, H. Ben Jannet. P. J. Abreu and Z. Mighri, J. Soc. Alg. Chim., 14, 181-187 (2004).

  36. “Alcools tetrahydropyraniques polyacetyleniques antibacteriens de la plante Rantherium suaveolens poussant dans le sud Tunisien” M. M. Oueslati, H. Ben Jannet. P. J. Abreu, and Z. Mighri, J. Soc. Alg. Chim., 14, 245-258 (2004).

  37. “Antioxidant Phenolic Glycosides from Moricandia arvensis”, Hatem Braham, Zine Mighri, Hichem Ben Jannet, Susan Matthew, and Pedro M. Abreu, Journal of Natural Products, 68, 517-522 (2005).

  38. “New Ceramides from Rantherium suaveolens”, M. Habib Oueslati, H. Ben Jannet, Zine Mighri, Pedro M. Abreu, Lipids, 40, 1075-1079 (2005).

  39. “QSAR analysis of phenolic antioxidant using MOLMAP descriptors of local properties”, Sunil Gupta, Susan Mathew, Pedro Abreu, and João Aires-de-Sousa, Biorg. Med. Chem., 14, 1199-1206 (2006).

  40. “Anti-inflammatory and antioxidant activity of a medicinal tincture from Pedilanthus tithymaloides”, Pedro Abreu, Susan Matthew,Tania González, David Costa, Marcela A. Segundo, and Eduarda Fernandes, Life Sciences, 78, 1578-1585 (2006).

  41. “New Macrocyclic Lathyrane Diterpenes, from Euphorbia lagascae, as Inhibitors of Efflux Pump of Tumour Cells”, Noélia Duarte, Joseph Molnár, Nora Gyémánt, Pedro M. Abreu, Maria José U. Ferreira, Planta Medica, 72, 162-168 (2006).

  42. “Long Chain Alkyl and Alkenyl Phenols from the Roots of Ozoroa insignis”, Yonghong Liu and Pedro J.M. Abreu, J. Braz. Chem. Soc., 17, 527-532 (2006).

  43. “Effect of extraction parameters on the chemical structure and gel properties of κ/ι-hybrid carrageenans obtained from Mastocarpus stellatus”, L. Hilliou, F.D.S. Laratonda, P. Abreu, A.M. Ramos, A.M. Sereno, M.P. Gonçalves, Biomolecular Engineering, 23, 201-208 (2006).

  44. “Euphoportlandols A and B, tetracylic diterpene polyesters from Euphorbia portlandica and their anti-MDR effects in cancer cells”, Ana M. Madureira, Nora Gyémánt, José R. Ascenso, Pedro M. Abreu, Joseph Molnár, and Maria-José U. Ferreira, Journal of Natural Products, 69, 950-953 (2006).

  45. “Tirucallane triterpenes from the roots of Ozoroa insignis”, Yonghong Liu and Pedro Abreu, Phytochemistry, 67, 1309-1315 (2006).

  46. “Heterocyclic terpenes: Linear furano- and pyrrolo-terpenoids”, Yonghong Liu, Si Zhang, P.J.M. Abreu, Natural Product Reports, 23, 630-651 (2006).

  47. “Phytochemical Constituents from Salsola tetrandra”, M. Habib Oueslati, Hichem Ben Jannet, Zine Mighri, J. Chriaa, and Pedro M. Abreu, Journal of Natural Products, 69, 1366-1369 (2006).

  48. “Ellagic acid glycosides from Turpinia ternata”, Susan Matthew, Kuo-Ching Kao, Yuan-Shiun Chang, Pedro M. Abreu, Natural Product Research, 21, 83-88 (2007).

  49. “Antioxidant compounds from Ebenus pinnata”, Hatem Braham, Hichem Ben Jannet, Zine Mighri, Susan Matthew, Pedro M. Abreu, Fitoterapia, 78, 32-34 (2007).

  50. “High-Performance Liquid Chromatographic Determination of Glycoalkaloids in Potatoes from Conventional, Integrated, and Organic Crop Systems” Pedro Abreu, Angela Relva, Susan Matthew, Zulmira Gomes, and Zilda Morais, Food Control, 18, 40-44 (2007).

  51. “Ozoroalide, a new orsellinic acid type macrolide from Ozoroa insignis”, Yonghong Liu, Pedro J.M. Abreu, Fitoterapia, 78, 388-389 (2007).

  52. “A new C9 nor-isoprenoid glucoside from Rantherium suaveolens”, M. Habib Oueslati, H. Ben Jannet, Zine Mighri, Susan Matthew, and Pedro M. Abreu, Natural Product Research 21, 884-888 (2007).

  53. “Antimalarial Flavonol Glycosides from Euphorbia hirta”, Y. Liu,  N. Murakami, H. Ji,  Pedro Abreu, S. Zhang, Pharmaceutical Biology, 45, 278-281 (2007).

  54. “Isolation and Identification of Antioxidants from Pedilanthus tithymaloides”, Pedro M. Abreu, Susan Matthew, Tania González, Lucie Vanickova, David Costa, Ana Gomes, Marcela A. Segundo, Eduarda Fernandes, J. Natural Medicines, 62, 67-70 (2008).

  55. “Antileishmanial activity of piceatannol isolated from Euphorbia lagascae seeds", Noélia Duarte, Oliver Kayser, Pedro Abreu, and Maria José U. Ferreira, Phytotherapy Research, 22, 455-457 (2008).

  56. “Saoussanabiloide, a novel antifungal alkaloid from Echiochilon fruticosum Desf. growing in Tunisia”, S. Hammami, N. Migrhi, H. Ben Jannet, N. Boughalleb, A. Zardi-Bergaoui, A. Nefzi, P. M. Abreu, Z. Mighri, Natural Product Research, 23, 1466-1471 (2009).

  57. “Effects of strictosamide on mouse brain and kidney Na+,K+-ATPase and Mg2+-ATPase activities”, M.F. Candeias, P. Abreu, A. Pereira, J. Cruz-Morais, Journal of Ethnopharmacology, 121, 117–122 (2009).

  58. “Composition and in vitro antioxidant effects of jellyfish Catostylus tagi from Sado estuary (SW Portugal)”, Z. B. Morais, A. M. Pintão, I. M. Costa, M. T. Calejo, N. M. Bandarra, Pedro Abreu, Journal of Aquatic Food Product Technology, 18, 90-107 (2009).

  59. “Phenolic constituents of Convolvulus dorycnium L flowers”, Sana Nacef, Hichem Ben Jannet, Pedro Abreu, Zine Mighri, Phytochemistry Letters, 3, 66–69 (2010).

  60. “The impact of seaweed life phase and 1 post-harvest storage duration on the chemical and rheological properties of hybrid carrageenans isolated from Portuguese Mastocarpus stellatu.”, Loic Hilliou, Fábio D.S. Larotonda, Pedro Abreu, Maria H. Abreu, Alberto M. Sereno, Maria P. Gonçalves, Carbohydrate Polymers 87, 2655–2663 (2012).


BOOK CHAPTERS

P. M. Abreu; P. Branco; S. Matthew, “Natural product-like combinatorial libraries towards the discovery of lead compounds”, in Combinatorial Synthesis of Natural Product Based Libraries, vol. 2, Ed. A. M Boldi, Combinatorial Chemistry Series, CRC Press, Chapt 11, 257-352, 2006.



P. J. M. Abreu; W. Heggie, “Terpenóides e esteróides”, in Biossíntese dos Produtos Naturais, Eds. A.M. Lobo e A.M. Lourenço, IST Press (2007).

Hendrik Luesch and Pedro Abreu, “A Natural Product Approach to Drug Discovery: Probing Modes of Action of Antitumor Agents by Genome-Scale cDNA Library Screening”, in Ligand-Macromolecular Interactions in Drug Discovery, Methods in Molecular Biology, vol. 572, Ed. A.C. Roque, The Humana Press Inc., Chapt 17, 261-277 (2010).

COMMUNICATIONS


  • "Research in Organic Chemistry at the FCT-UNL", University of Namur, Belgium (1980).

  • "Isolation of natural products from Pisolithus tinctorius", Instituto Superior Técnico, Lisbon (1981).

  • "Chemical constituents of Pisolithus tinctorius", P.Macedo de Abreu, A.M.Lobo, L.S.Godinho, 7th Meeting of the Portuguese Chemical Society, Lisbon (1984).

  • "Novel triterpenoids from the fungus Pisolithus tinctorius", Ana Lobo, P. Macedo de Abreu, S.Prabhakar, L.S.Godinho, H.S.Rzepa, R.N.Sheppard, 8th Meeting of the Portuguese Chemical Society, Braga (1985).

  • "Novel triterpenoids from the fungus Pisolithus tinctorius", A.M.Lobo, P.Macedo de Abreu, S.Prabhakar, L.S.Godinho, D.J.Williams, 9th Meeting of the Portuguese Chemical Society, Coimbra (1986).

  • "Chemical study of the fungus Pisolithus tictorius", FCT-UNL (1986).

  • "Novel triterpenoids from the fungus Pisolithus tinctorius", University of Tokyo (1987).

  • "Novel triterpenoids from the fungus Pisolithus tinctorius", Pedro M.Abreu, Ana M.Lobo, Sundaresan Prabhakar, 16th Intenational Symposium on the Chemistry of Natural Products (IUPAC), Kyoto (1988).

  • "Brassinosteroids", FCT-UNL (1988).

  • "Brassinosteroids: chemistry, physiology and agriculture aplications", LNETI, Lisbon (1988).

  • "Halogenated monoterpenos from the algae Plocamium cocciuneum, from the portuguese coast”, Pedro Abreu and José Galindro, National Meeting of Macroalgae, LNETI, Lisbon (1990).

  • "Brassinosteróides, a new class of phyto-hormones", CSIC, Madrid (1990).

  • "Natural products of the red alga Plocamium coccineum and Porphyra umbilicalis", Pedro Abreu, José Galindro, 12th Meeting of the Portuguese Chemical Society, Coimbra (1991).

  • "Isolation and identification of Brassinosteroids", University of Brussels, (1993).

  • "Reverse phase LPLC and HPLC isolation of meliacines from Khaya senegalensis LPLC", Pedro Abreu, 14th Meetingº of the Portuguese Chemical Society, Aveiro (1994).

  • "Stereochemical elucidation of cyclic halogenated monoterpenes by Nuclear Overhauser Effect”, José M.Galindro and Pedro Abreu, 14th Meetingº of the Portuguese Chemical Society, Aveiro (1994).

  • "Characterization of 2-O--galactopyranosilglycerol from Gelidium sesquipedale", Maria H.Luís, Angela M. Relva and Pedro Abreu, 14th Meeting of the Portuguese Chemical Society, Aveiro (1994).

  • "Medicinal plants from Guiné-Bissau", Pedro Abreu and Eurico S.Martins, 14th Meeting of the Portuguese Chemical Society, Aveiro (1994).

  • "Halogenated monoterpenes from Plocamium cartilagineum from the portuguese coast", José M.Galindro and Pedro Abreu, 14th Meeting of the Portuguese Chemical Society, Aveiro (1994).

  • "Flavonoids from Tephrosia uniflora", Maria H.Luís and Pedro Abreu, 14th Meeting of the Portuguese Chemical Society, Aveiro (1994).

  • "A phytochemical survey on medicinal plants of Guinea-Bissau", International Congress on Natural Products Research (American Society of Pharmacognosy), Halifax (1994).

  • "Chemical constituents of Parkia biglobosa", M.E.M.Araújo, F.M.S.B.Palma, A.T.Moutinho, 43th Annual Congress of the Society for Medicinal Plant Research, Halle, RFA (1995).

  • “Triterpenoids from the fungus Pisolithus tinctorius”, University of Thessaloniki (1996).

  • “Contribution to the knowledge of some medicinal plants from Guiné-Bissau”, Eurico S. Martins, Pedro Abreu and Umaru Candé, Symposium of Tropical Agriculture and Agro-
    -Industry, Congress of Engineering of the African Countries of Portuguese Official Language, Lisbon (1996).

  • “Volatile constituents of the rhizomes of Aframomum alboviolaceum (Ridley) K. Schum. from Guinea-Bissau”, Pedro M. Abreu and Rita G. Noronha, 44th Annual Congress of the Society for Medicinal Plant Research, Praha (1996).

  • “Triterpenoids from Leguminosae Detarium microcarpum and Pterocarpus erinaceus from Guinea-Bissau”, M.Eduarda Araújo, A.B.Canda, Ana M.Lourenço, Rita G.Noronha and Pedro M.Abreu, 44th Annual Congress of the Society for Medicinal Plant Research, Praha (1996).

  • “The magic potion of the healer Umaru Seidi from Guinea-Bissau”, FCT/UNL (1997).

  • “Characterisation of triterpene alcohol from Combretum micranthum”, Inês Eleutério, Marta Andrade, Bruno Vitoriano, Elisabete Mateus, Isabel Castanheira, Carmo Almeida and Pedro Abreu”, 2º National Meeting of Organic Chemistry, Portuguese Chemical Society (Oeiras, 1997).

  • “New metabolites from Plocamium cartilagineum from the Portuguese coast”, Pedro Abreu and José M. Galindro, 2º National Meeting of Organic Chemistry, Portuguese Chemical Society (Oeiras, 1997).

  • “Chemical composition of Lactarius controversus, a basidiomycetes fungus”, Pedro Abreu, Maria E. Araújo, Tatiana Fonseca and Susana P. Santos, 45 th Annual Congress of the Society for Medicinal Plant Research Regensburg, Germany (1997).

  • “Phenylpropanoids from endemic Umbellifereae of portuguese islands”, A. Antunes, T. Fonseca, M.O. Almeida, S. Gaudêncio, P. Abreu, M.E. Araújo, S.P. dos Santos, International Symposium on Bioassay Methods in Natural Product Research and Drug Development, Uppsala, Sweden (1997).

  • "A new indole alkaloid from Sarcocephalus latifolius", Pedro M. Abreu, António Pereira, International Symposium on Structure and Biosynthesis of Isoquinoline, Indole and Related Alkaloids, Istanbul, Turkey (1998).

  • "Antimicrobial, antitumor and antileishmania screening of medicinal plants from Guinea-Bissau", P. M. Abreu, O. Kayser, K.-U. Bindseil, K. Siems and A. Seemann, 46 th Annual Congress of the Society for Medicinal Plant Research Regensburg, Vienna (1998).

  • "Screening for bioactive compounds from medicinal plants from Guinea-Bissau", P. M. Abreu, O. Kayser, K.-U. Bindseil, K. Siems and A. Seemann, 21 st Intenational Symposium on the Chemistry of Natural Products (IUPAC), Beijing (1998).

  • "Natural Products from Plants", Pedro M. Abreu, Ana Lourenço, Luísa Ferreira, Ali Loukaci, António M.D.L. Pereira, Patrícia Máximo, Enconto REQUINTE, Porto (1999).

  • “Bioguided isolation of natural products from medicinal plants from Guinea-Bissau”, Pedro Abreu, 3th National Meeting of Organic Chemistry, Portuguese Chemical Society, Covilhã (1999).

  • “New trichothecenes isolated from Holarrhena floribunda stem”, Ali Loukaci and Pedro Abreu, Meeting of the Phytochemical Society of Europe, “2000 Years of Natural Products Research-Past, Present and Future”, Amsterdam (1999).

  • “Antileishmania and immunostimulating activities of dimeric proanthocyanidins from Khaya senegalensis”, O. Kayser and Pedro Abreu, Meeting of the Phytochemical Society of Europe, “2000 Years of Natural Products Research-Past, Present and Future”, Amsterdam (1999).

  • “Studies on chemical components of mushrooms”, Pedro Abreu, M. Eduarda Araújo, Susana Pina dos Santos, Fernando Toscano, Meeting of the Phytochemical Society of Europe, “2000 Years of Natural Products Research-Past, Present and Future”, Amsterdam (1999).

  • “Characterisation of a sugar fraction from Sarcocephalus latifolius stem bark extract”, António Pereira, Pedro Abreu and Angela Relva, 3th International Meeting of the Portuguese Carbohydrate Chemistry Group, Aveiro (1999).

  • "Antileishmanial and antiplasmodial activity of trichothecenes from Holarrhena floribunda", O. Kayser, P. M. Abreu and R. Brun, 22 st Intenational Symposium on the Chemistry of Natural Products (IUPAC), S. Carlos, Brasil (2000).

  • "Two indole alkaloids from Sarcocephalus latifolius”, Pedro M. Abreu and António Pereira, 22 st Intenational Symposium on the Chemistry of Natural Products (IUPAC), S. Carlos, Brasil (2000).

  • "Medicinal Plants of Tunisia. Natural Products from Prasium majus and Periploca laevigata", P. Abreu, F. Hichri, M.A. Mahjoub, H. Ben Jannet, O. Hammouda and Z. Mighri, 4h National Meeting of Organic Chemistry, Portuguese Chemical Society, Coimbra (2001).

  • "Carbohydrates from Detarium microcarpum Bark Extracts", Pedro Abreu and Angela Relva, 4h International Meeting of the Portuguese Carbohydrate Chemistry Group, Lisbon (2001).

  • "Pharmacological effects of strictosamide on Charles River mice", J.M.C. Morais, F. Candeiasa A. Pereira and P. Abreu, 50th Annual Congress of the Society for Medicinal Plant Research Regensburg, Barcelone (2002).

  • "Antioxidant and antileishmanial activity of piceatannol", N. Duarte , M. E. Figueira , H. Mota-Filipe , O. Kayser, P. M. Abreu , M. Castro and M. J. Ferreira , 50th Annual Congress of the Society for Medicinal Plant Research Regensburg, Barcelone (2002).

  • "Study of the secondary metabolites of the methanol extract of Euphorbia pubescens. Evaluation of their antibacterial activity", C. Valente, A. Duarte , J. R. Ascenso , P. M. Abreu and M. J. U. Ferreira, 50th Annual Congress of the Society for Medicinal Plant Research Regensburg, Barcelone (2002).




  • "A new macrocycle lathyrane type diterpene and other diterpenoids from Euphorbia lagascae", N. Duarte, P. Abreu and M.J.U. Ferreira, 51th Annual Congress of the Society for Medicinal Plant Research Regensburg, Kiel (2003).




  • "A new macrocycle diterpene that modulates multidrug resistance mediated by P-glycoprotein", C. Valente, M. J.U. Ferreira, P.M. Abreu, N. Guémánt, K. Ugocsai, J. Hohmann and J. Molnár, 51th Annual Congress of the Society for Medicinal Plant Research Regensburg, Kiel (2003).




  • "Po

lycyclic rearranged jatrophane derivatives from Euphorbia portlandica", A.M. Madureira, J.R. Ascendo. P. Abreu and M.J.U. Ferreira, 51th Annual Congress of the Society for Medicinal Plant Research Regensburg, Kiel (2003).



  • "A stilbene with antileishmanial activity. Preparation of methylated derivatives", N. Duarte, P. Abreu, M.J. Ferreira, XIII Congresso Nacional da Sociedade Española de Quimica Terapeutica, Santiago de Compostela (2003).

  • "Antibacterial activity screening of terpenic compounds isolated from Euphorbia lagascae", N. Duarte, A. Duarte, P. Abreu, M.J. Ferreira, XIII Congresso Nacional da Sociedade Española de Quimica Terapeutica, Santiago de Compostela (2003).

  • "Structure elucidation of two macrocyclic diterpenes by NMR", C. Valente, J.R. Ascendo. P.M. Abreu, M.J.U. Ferreira, 2nd Portuguese-Brazilian NMR Conference, Sintra (2003).

  • "HPLC determination and preparative isolation of glycoalkaloids from Solanum turerosum", Pedro Abreu, Angela Relva, Susan Matthew, Zulmira Gomes, Zilda Morais, 3º Encontro Nacional de Cromatografia, SPQ , Lisboa (2003).

  • “Phytochemistry of Tunisian plants. Natural products from Rantherium suaveolens”, P. J. M. Abreu, M.H. Oueslati, H. Ben Jannet, Z. Mighri, V International Congress of Chemistry and Chemical Engeneering, Havana (2004).

  • “Phytochemistry of Tunisian plants. Glucosides and fructofuranosedes from Moricandia arvensis”, P. J. M. Abreu, H. Braham, H. Ben Jannet, Z. Mighri, V International Congress of Chemistry and Chemical Engeneering, Havana (2004).

  • “Bioassay-guided isolation of natural products: highlights on current research”, P. J. M. de Abreu and M. J. U. Ferreira, V International Congress of Chemistry and Chemical Engeneering, Havana (2004)

  • “Anti-inflammatory and antioxidant activity of the medicinal extract of Pedilanthus tithymaloides”, P. J. M. Abreu, S. Chacko, T.L. Gozález, E. Fernandes, D. Costa, J. L. F. C. Lima, V International Congress of Chemistry and Chemical Engeneering, Havana (2004).

  • “HPLC determination of glycoalkaloids in commercial varieties of Portuguese potatoes”, Pedro Abreu, Angela Relva, Susan Matthew, Zulmira Gomes, Zilda Morais, 27th International Symposium on capillary chromatography, Riva del Garda (2004).

  • “Antiviral activity of terpenoids against Herpes simplex viruses”, N. Duarte, N. Antunes, C. Ramalhete, M.L. Valdeira, P. M. Abreu, M. J. U. Ferreira, XIX Meeting of the Portuguese Chemical Society, Coimbra (2004).

  • “A new abietane quinine diterpene and a new sesquiterpene-coumarin ether from Euphorbia portlandica”, A. N. Madureira, P. M. Abreu, M. J. U. Ferreira, XIX Meeting of the Portuguese Chemical Society, Coimbra (2004).

  • “New macrocyclic diterpenes and their effects in vitro on human cancer cell lines”, C. Valente, M. Pedro, J. R. Ascenso, M. S. J. Nascimento, P. M. Abreu, M. J. U. Ferreira, XIX Meeting of the Portuguese Chemical Society, Coimbra (2004).

  • “HPLC Determination of Glycoalkaloids in Commercial Varieties of Portuguese Potatoes”, P. Abreu; A. Relva; S. Matthew; Z. Gomes; Z. Morais, 3º Encontro REQUIMTE, Fátima (2004).

  • “Isolation of Bioactive Natural Products: from Plants: Highlights on Current Research”, P. Abreu, 3º Encontro REQUIMTE, Fátima (2004).

  • “HPLC determination of glycoalkaloids in commercial varieties of Portuguese potatoes”, Pedro Abreu, Angela Relva, Susan Matthew, Zulmira Gomes, Zilda Morais, 27th International Symposium on capillary chromatography, Food Protection International Conference, CES Egas Moniz, Monte da Caparica (2004).

  • “Viscoelastic characterization of carrageenan solutions and gels obtained from Portuguese seaweeds”, L. Hilliou, P. Abreu, A.M. Ramos, A.M. Sereno and M.P. Gonçalves, IBEREO 2004-Iberia Rheology Meeting, Beja (Portugal) (2004).

  • “Isolation and characterizarion of two new polycyclic jatrophane derivatives from Euphorbia portlandica, evaluation of their ability to inhibit P.glycoprotein transport function”, A. M. Madureira, N. Gyémánt, J. Molnár, P. M. Abreu, and M. J. U. Ferreira, 2nd Congress of the Portuguese Society of Pharmaceutical Sciences, Coimbra (2005).

  • “Ellagic acid derivatives from Turpinia ternate”, Susan Matthew, Kuo-Ching Kao, Pedro Abreu, Nordic Natural Products Meeting – Pharmacognosy and Chemistry, Tjärnö, Sweden (2005).

  • “Antioxidant compounds from Ebenus pinnata”, H. Braham, Susan Matthew, H.B Jannet, Z. Mighri, Pedro M.Abreu, Nordic Natural Products Meeting – Pharmacognosy and Chemistry, Tjärnö, Sweden (2005).

  • “Effect of chemical extraction parameters on the linear and non linear rheological properties of carrageenan gels”, L. Hilliou, F.D.S. Larotonda, P. Abreu, A.M. Ramos, A.M. Sereno and M.P.Gonçalves, Annual European Rheology Conference, Grenoble, France (2005).

  • “Effect of seasonal variation on the chemical and physical properties of carrageenans extracted from Mastocarpus Stellatus”, Loic Hilliou, Fábio D.S. Larotonda, Ana M. Ramos, Pedro M. Abreu, Maria do Pilar Gonçalves, Alberto M. Sereno, 9th International Chemical Engineering Conference, Porto (2005).

  • “Chemical and physical characterization of biopolymers extracted from Portuguese carrageenophyte seaweeds”, L. Hilliou, F.D.S. Larotonda, P. Abreu, A.M. Ramos, A.M. Sereno and M.P.Gonçalves, 2nd MERCOSUR Congress on Chemical Engineering, 4th MERCOSUR Congress on Process Systems Engineering, EMPROMER 2005, Rio de Janeiro, Brasil, (2005).

  • “Long chain alkyl phenols, and a new macrolide from the roots of Ozoroa insignis”, Yonghong Liu and Pedro Abreu, Phytotherapy - the role of an ancient tradition in modern times, Phytochemical Society of Europe, Funchal (2005).

  • “Anti-inflammatory and antioxidant activity of a Pedilanthus tithymaloides tincture used in Cuban traditional medicine”, Tania L. González, Pedro Abreu, Susan Matthew, David Costa, Marcela A. Segundo, and Eduarda Fernandes, Phytotherapy - the role of an ancient tradition in modern times, Phytochemical Society of Europe, Funchal (2005).

  • “GCMS characterization of cardanols and ginkgolic acids from the roots of Ozoroa insignis”, Yonghong Liu and Pedro Abreu, 4º Encontro Nacional de Cromatografia, SPQ, Évora (2005).

  • “Hopanoid composition from miocene sediment samples (lower Tagus bassin, Portugal) by GCMS”, H. Coelho, João Pais, P.A.R.R. legoinha, P. Abreu, and Angela Relva, 4º Encontro Nacional de Cromatografia, SPQ, Évora (2005).

  • “Evaluation of three new macrocyclic lathyrane diterpenes from Euphorbia lagascae on the reversal of multidrug resistance on mouse lymphoma cells”, N. Duarte, A. Gonçalves, N. Gyémánt, J. Molnár, P. Abreu and M. J. U. Ferreira. 53th Annual Congress of the Society for Medicinal Plant Research, Florença, (2005).

  • “Gossypitrin: the antiasthmatic principle isolated from the flowers of Tallipariti ellatum, and an approach to its possible mechanism of action”, J.G. Yaque, A.Cuéllar, Pedro Abreu, Cuba-UK Symposium on Chemistry and Life Sciences, Havana (2006).

  • “Antioxidant and anti-inflammatory phenolics from Pedilanthus tithymaloides”, Pedro Abreu, Susan Matthew, Tania González, David Costa, Marcela Segundo and Eduarda Fernandes, 54th Annual Meeting of the Society for Medicinal Plant Research, Helsinki (2006).

  • “Bioguided isolation of natural products: highlights on current research”, Pedro Abreu, invited conferencist, UANL International Symposium on Natural Products, Monterrey, Mexico (2006).

  • “Bioassay-guided isolation of antioxidant and anti-inflammatory compounds from Pedilanthus tithymaloides”, González T.L., Abreu P., Matthew S. Costa D., Segundo, M., and Fernandes E., FAPRONATURA, First Symposia about Pharmacology of Natural Products, Varadero, Cuba (2006).

  • “Natural products from African and Caribbean medicinal plants: highlights on current research”, Pedro Abreu, 7th National Meeting of Organic Chemistry, Portuguese Chemical Society (Lisbon, 2007).




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